Subthalamic Nucleus Stimulation May Be Effective in Severe OCD, but Safety a Concern Preliminary findings suggest that subthalamic nucleus stimulation may be effective in treating severe, refractory obsessive-compulsive disorder. However, the procedure is also associated with an increased risk for serious adverse events. Medscape Medical News |
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ASHG 2008: Gaucher Disease Mutation Carriers at Higher Risk for Parkinson's Disease A multiethnic study on 4 continents found that glucocerebrosidase gene mutations are the most common genetic risk factor for Parkinson's disease. Medscape Medical News |
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Growth Hormone Secretagogue MK-677 Ineffective in Alzheimer's Disease A randomized trial of MK-677, a growth hormone secretagogue, shows no benefit for patients with Alzheimer's disease, despite successfully increasing serum insulinlike growth factor-1, the treatment target in this trial. Medscape Medical News |
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Imaging Study Provides Strong Support for Cognitive-Reserve Hypothesis A new imaging study looking at plaque burden in the brains of individuals with and without dementia strongly supports the long-held cognitive-reserve hypothesis, that those with more education are better able to withstand Alzheimer's disease pathology. Medscape Medical News |
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Frequency of Stimulant Treatment and of Stimulant-Associated Mania/Hypomania in Bipolar Disorder Patients This study examines the effects of stimulant treatment in bipolar disorder patients. Psychopharmacology Bulletin |
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Failed Connections: Why Connecting Humans Is as Important as Connecting Computers Daniel Z. Sands, MD, MPH, of Cisco and Harvard Medical School, explains why we need to learn to communicate better.
The Medscape Journal of Medicine |
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Frequency of Stimulant Treatment and of Stimulant-Associated Mania/Hypomania in Bipolar Disorder Patients This study examines the effects of stimulant treatment in bipolar disorder patients.
Psychopharmacology Bulletin |
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AHA 2008: Negative Thinking Predicts Depression in Heart-Failure Patients Negative thinking may play a major role in the development of depression in patients with heart failure, new research suggests. Medscape Medical News |
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Experts Identify New Risk Factors for Perioperative Death and Stroke In the most clinically detailed population-based study of carotid endarterectomy to date, researchers outline 11 risk factors for poor outcomes, and the results may influence guideline updates. Medscape Medical News |
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Urban Carotid Endarterectomy Patients Have More Risk Factors, Worse Outcomes Urban carotid endarterectomy (CEA) patients currently bear a higher risk factor burden and face worse outcomes than those reported in earlier clinical trials, according to a findings published in the November issue of Stroke. Reuters Health Information |
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